Breaching the blood-brain barrier: Researchers may have solved 100-year-old puzzle

14 09 2011

This is immense news that could revolutionize pharmacology:

Finding May Permit Drug Delivery to the Brain for Alzheimer’s, Multiple Sclerosis and Brain Cancers

Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer’s disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered.

The researchers found that adenosine, a molecule produced by the body, can modulate the entry of large molecules into the brain. For the first time, the researchers discovered that when adenosine receptors are activated on cells that comprise the blood-brain barrier, a gateway into the blood-brain barrier can be established.

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One response

14 09 2011

Alzheimer’s has been recently characterized as hugely overdiagnosed. Most people with “Alzheimer’s” on biopsy show no signs of lesions or plaques and, thus, suffer from simple memory decline, and most of the drugs developd for Alzheimer’s are irrelevant.

By the way, you should check out the next monograph by American Herbal Pharmacopoeia on American gintseng root. This stuff has amazing activity in some of the issues that you mention here.

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